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Correction: Histone demethylase KDM6B promotes epithelial-mesenchymal transition.

      VOLUME 287 (2012) PAGES 44508–44517
      In Fig. 1A, the wrong image for the control group was presented. The authors inadvertently cropped the control images in Fig. 1, A and E, from the same raw image. Fig. 1A has now been corrected and does not affect the results or conclusions of the work. The authors sincerely apologize for their mistake during figure preparation and for any inconvenience this may have caused readers.

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      • Histone Demethylase KDM6B Promotes Epithelial-Mesenchymal Transition
        Journal of Biological ChemistryVol. 287Issue 53
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          Background: TGF-β induces EMT to regulate tumor invasion and metastasis. Results: TGF-β induces KDM6B and promotes EMT by activating SNAI1 via removing H3K27me3 marks. Conclusion: KDM6B is required for TGF-β-induced EMT and breast cancer cell invasion. Significant: Our findings highlight a novel epigenetic mechanism regulating EMT and cancer cell invasion and have potential implications in targeting metastatic breast cancer.
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