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Neutralizing interleukin 1β (IL-1β) induces β-cell survival by maintaining PDX1 protein nuclear localization.

Open AccessPublished:November 13, 2015DOI:https://doi.org/10.1074/jbc.A110.210526
      VOLUME 286 (2011) PAGES 17144–17155
      This article has been retracted by the publisher. Fig. 1E contained images that had been reused from the following references (Glas, R., Sauter, N. S., Schulthess, F. T., Shu, L., Oberholzer, J., and Maedler, K. (2009) Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and β cell function and survival. Diabetologia 52, 1579–1588 and Maedler, K., Schumann, D. M., Sauter, N., Ellingsgaard, H., Bosco, D., Baertschiger, R., Iwakura, Y., Oberholzer, J., Wollheim, C. B., Gauthier, B. R., and Donath, M. Y. (2006) Low concentration of interleukin-1β induces FLICE-inhibitory protein-mediated β-cell proliferation in human pancreatic islets. Diabetes 55, 2713–2722), and these reused images represented different experimental conditions.