- Moshous D.
- Callebaut I.
- de Chasseval R.
- Corneo B.
- Cavazzana-Calvo M.
- Le Deist F.
- Tezcan I.
- Sanal O.
- Bertrand Y.
- Philippe N.
- Fischer A.
- de Villartay J.P.
Oligonucleotides and DNA Substrates
Protein Expression and Purification
Biochemical Nuclease Assay
Artemis Can Resect Blunt DNA Ends But at a Much Slower Rate Than at DNA Overhangs
Artemis Endonuclease Activity on Blunt DNA Ends Is Strictly Dependent on DNA-PKcs and ATP and Is Modulated by Ku
Titration Reveals That DNA-PKcs Can Be Inhibitory at High Concentrations
The Blunt End DNA Sequence Determines the Extent to Which Ku and DNA-PKcs Stimulate the 5′ Nuclease Action of Artemis
Artemis 3′ Endonuclease Resection Does Not Show Substantial Sequence Dependence but Is Stimulated by DNA-PKcs and Ku
5′ Resection Occurs Prior to 3′ Resection on Blunt DNA Ends
Artemis Resection Progresses Internally along the DNA with Time
Unifying Kinetic Features for Artemis Action at DNA Ends
A Unifying Physical Model for Artemis Nuclease Activity at DNA Ends
The 5′ Exonuclease of Artemis
The Role of DNA-PKcs and Ku in Artemis Interaction with Its Substrate
Biological Implications of the Unified Model of Artemis Nuclease Action for NHEJ
Biological Implications of the Unified Model of Artemis Nuclease Action for V(D)J Recombination
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