Highlights of 2016

Virtual Issue: Drug metabolism, transport and toxicity

The editors at JBC are pleased to present this collection of papers as our "Highlights of 2016," including new chemical and genetic tools to probe receptor and inflammasome function, insights into the consequences of physical properties such as membrane curvature and contractility, and new molecular details of cellular reprogramming, microbial pathogenesis and the first pannexin-linked disease. While no group this small can fully capture the extent of exciting advances and new insights published in more than 2100 JBC papers in the past year, these articles are emblematic of the exciting and significant studies across the breadth of JBC’s scientific scope. The Highlights of 2016 are freely available - download and read them today!

The cover art shows a collage of lipid droplet fusion and growth induced by CIDE proteins (explored by Xu et al.), platelet progenitors expressing the neuronal biomarker BDNF (reported by Chacón-Fernández et al.) and a model of the pannexin channel (as investigated by Shao et al). Artwork created by Valery Masterson.

Download PDF: Highlights of 2016

Assembled by the editors of JBC; published February 2017

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Cell Biology

Computational Biology

Developmental Biology

DNA and Chromosomes


Gene Regulation

Genomics and Proteomics

Glycobiology and Extracellular Matrices



Membrane Biology


Methods and Resources

  • Vadim N. Gladyshev, Elias S. Arnér, Marla J. Berry, Regina Brigelius-Flohé, Elspeth A. Bruford, Raymond F. Burk, Bradley A. Carlson, Sergi Castellano, Laurent Chavatte, Marcus Conrad, Paul R. Copeland, Alan M. Diamond, Donna M. Driscoll, Ana Ferreiro, Leopold Flohé, Fiona R. Green, Roderic Guigó, Diane E. Handy, Dolph L. Hatfield, John Hesketh, Peter R. Hoffmann, Arne Holmgren, Robert J. Hondal, Michael T. Howard, Kaixun Huang, Hwa-Young Kim, Ick Young Kim, Josef Köhrle, Alain Krol, Gregory V. Kryukov, Byeong Jae Lee, Byung Cheon Lee, Xin Gen Lei, Qiong Liu, Alain Lescure, Alexei V. Lobanov, Joseph Loscalzo, Matilde Maiorino, Marco Mariotti, K. Sandeep Prabhu, Margaret P. Rayman, Sharon Rozovsky, Gustavo Salinas, Edward E. Schmidt, Lutz Schomburg, Ulrich Schweizer, Miljan Simonović, Roger A. Sunde, Petra A. Tsuji, Susan Tweedie, Fulvio Ursini, Philip D. Whanger, Yan Zhang
    Published online: September 19, 2016


Molecular Bases of Disease

Molecular Biophysics


Plant Biology

Protein Structure and Folding

Protein Synthesis and Degradation


Signal Transduction