Virtual issue: Coronaviruses
Coronavirus typically causes mild respiratory infections in humans and other animals, but several serious outbreaks of new family members in the last 20 years have elevated the urgency of understanding and interrupting its replication and transmission. From SARS to MERS, it is important to remind ourselves what was learned from studies of the previous outbreak strains to prevent direct duplication of past work and build more quickly toward therapeutic endpoints against SARS-CoV-2 and future strains. To this end, the editors at JBC present a collection of coronavirus content, building from the first outbreaks in 2003, and updated through the 2019-nCoV pandemic. While the author versions of the research papers are always freely available, as with all JBC content, the redacted versions of these articles are also free. We hope these articles enable and inspire researchers working on SARS-CoV-2 and other deadly viruses, for the good of all.
The cover art shows a coronavirus entering the lungs, surrounded by mucus, antibodies, and immune system proteins. Illustration by David S. Goodsell, RCSB Protein Data Bank, doi: 10.2210/rcsb_pdb/goodsell-gallery-019. Artwork by Lisa Schnabel.
Assembled by Craig Cameron; published February 2020; updated July 2020