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July 10, 2009

Volume 284Issue 28p18557-19152, e99931
Open Access
On The Cover: View down the four-helix bundle to the diiron active site of the castor desaturase mutant T199D, which displays decreased desaturation activity and increased oxidase functionality consistent with that of its hypothesized ancestor. The non-coordinating residue on the lower left is Asp199. For details see the article by Shanklin et al., pages 18559–18563....
On The Cover: View down the four-helix bundle to the diiron active site of the castor desaturase mutant T199D, which displays decreased desaturation activity and increased oxidase functionality consistent with that of its hypothesized ancestor. The non-coordinating residue on the lower left is Asp199. For details see the article by Shanklin et al., pages 18559–18563.

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