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September 2018

Volume 293Issue 36p13768-14191
Open Access
On The Cover: Mice harboring a Notch3 mutation replicating the one associated with lateral meningocele syndrome exhibit pronounced osteopenia, increased osteoblasts, and osteocytes secreting RANKL and inducing osteoclast differentiation. The image shows bone rich in osteocytes (blue nuclei) embedded in the matrix and osteoblasts on trabecular surfaces that, by secreting RANKL, induce the formation of multinucleated bone-resorbing osteoclasts (red cytoplasm). For details, see the article by Canalis et al., pages 14165–14177....
On The Cover: Mice harboring a Notch3 mutation replicating the one associated with lateral meningocele syndrome exhibit pronounced osteopenia, increased osteoblasts, and osteocytes secreting RANKL and inducing osteoclast differentiation. The image shows bone rich in osteocytes (blue nuclei) embedded in the matrix and osteoblasts on trabecular surfaces that, by secreting RANKL, induce the formation of multinucleated bone-resorbing osteoclasts (red cytoplasm). For details, see the article by Canalis et al., pages 14165–14177.

Editors' Picks Highlights

Editors' Picks

Thematic Minireviews

Accelerated Communications

Cell Biology

Enzymology

Gene Regulation

Glycobiology and Extracellular Matrices

Immunology

Lipids

Metabolism

Methods and Resources

Microbiology

Molecular Bases of Disease

Molecular Biophysics

Neurobiology

Plant Biology

Protein Structure and Folding

Protein Synthesis and Degradation

Signal Transduction

Additions and Corrections

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