March 13, 2009
Volume 284Issue 11p6585-7404, e99908
Open Access
On The Cover: This image depicts the four key residues responsible for the morphogenic activity
of epimorphin/syntaxin-2; mutation of these amino acids removes the functional ability
of this protein. The highly homologous molecule syntaxin-1a was found to have no morphogenic
activity; mutation of the same four amino acids in syntaxin-1a to those found in epimorphin
reconstituted the morphogenic activity onto the inactive template. For details see
the article by Chen et al., pages 6877–6884....Show more
On The Cover: This image depicts the four key residues responsible for the morphogenic activity
of epimorphin/syntaxin-2; mutation of these amino acids removes the functional ability
of this protein. The highly homologous molecule syntaxin-1a was found to have no morphogenic
activity; mutation of the same four amino acids in syntaxin-1a to those found in epimorphin
reconstituted the morphogenic activity onto the inactive template. For details see
the article by Chen et al., pages 6877–6884.
