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March 13, 2009

Volume 284Issue 11p6585-7404, e99908
Open Access
On The Cover: This image depicts the four key residues responsible for the morphogenic activity of epimorphin/syntaxin-2; mutation of these amino acids removes the functional ability of this protein. The highly homologous molecule syntaxin-1a was found to have no morphogenic activity; mutation of the same four amino acids in syntaxin-1a to those found in epimorphin reconstituted the morphogenic activity onto the inactive template. For details see the article by Chen et al., pages 6877–6884....
On The Cover: This image depicts the four key residues responsible for the morphogenic activity of epimorphin/syntaxin-2; mutation of these amino acids removes the functional ability of this protein. The highly homologous molecule syntaxin-1a was found to have no morphogenic activity; mutation of the same four amino acids in syntaxin-1a to those found in epimorphin reconstituted the morphogenic activity onto the inactive template. For details see the article by Chen et al., pages 6877–6884.

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Enzyme Catalysis and Regulation

Mechanisms of Signal Transduction

Protein Synthesis, Post-Translational Modification, and Degradation

Mechanisms of Signal Transduction

Enzyme Catalysis and Regulation

Protein Synthesis, Post-Translational Modification, and Degradation

Mechanisms of Signal Transduction

Enzyme Catalysis and Regulation

Molecular Basis of Cell and Developmental Biology

Mechanisms of Signal Transduction

Transcription, Chromatin, and Epigenetics

Enzyme Catalysis and Regulation

Molecular Basis of Cell and Developmental Biology

Mechanisms of Signal Transduction

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Mechanisms of Signal Transduction

Transcription, Chromatin, and Epigenetics

Glycobiology and Extracellular Matrices

Metabolism and Bioenergetics

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Membrane Transport, Structure, Function, and Biogenesis

Protein Synthesis, Post-Translational Modification, and Degradation

Transcription, Chromatin, and Epigenetics

Protein Synthesis, Post-Translational Modification, and Degradation

Membrane Transport, Structure, Function, and Biogenesis

Protein Structure and Folding

Enzyme Catalysis and Regulation

Membrane Transport, Structure, Function, and Biogenesis

Molecular Basis of Cell and Developmental Biology

Protein Synthesis, Post-Translational Modification, and Degradation

Mechanisms of Signal Transduction

Protein Structure and Folding

Membrane Transport, Structure, Function, and Biogenesis

Enzyme Catalysis and Regulation

Molecular Basis of Cell and Developmental Biology

Membrane Transport, Structure, Function, and Biogenesis

Protein Structure and Folding

Transcription, Chromatin, and Epigenetics

Protein Synthesis, Post-Translational Modification, and Degradation

Enzyme Catalysis and Regulation

Mechanisms of Signal Transduction

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Enzyme Catalysis and Regulation

Molecular Basis of Cell and Developmental Biology

Metabolism and Bioenergetics

Glycobiology and Extracellular Matrices

Transcription, Chromatin, and Epigenetics

Mechanisms of Signal Transduction

Molecular Basis of Cell and Developmental Biology

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Transcription, Chromatin, and Epigenetics

Protein Structure and Folding

Protein Synthesis, Post-Translational Modification, and Degradation

Metabolism and Bioenergetics

Mechanisms of Signal Transduction

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Metabolism and Bioenergetics

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Protein Structure and Folding

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Membrane Transport, Structure, Function, and Biogenesis

Mechanisms of Signal Transduction

Glycobiology and Extracellular Matrices

Protein Structure and Folding

Glycobiology and Extracellular Matrices

Enzyme Catalysis and Regulation

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Membrane Transport, Structure, Function, and Biogenesis

Additions and Corrections

Papers of the Week

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