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September 13, 2019

Volume 294Issue 37p13527-13851
Open Access
On The Cover: The first crystal structure of a HIPK kinase reveals a unique conformation of the CMGC insert region in HIPK2 and features an inhibitor in the kinase active site. The structure, which also captures a regulatory phosphorylation site, provides a platform for future design of HIPK2-specific therapeutics for treatments of cancer and fibrosis. For details, see the article by Jura et al., pages 13545–13559....
On The Cover: The first crystal structure of a HIPK kinase reveals a unique conformation of the CMGC insert region in HIPK2 and features an inhibitor in the kinase active site. The structure, which also captures a regulatory phosphorylation site, provides a platform for future design of HIPK2-specific therapeutics for treatments of cancer and fibrosis. For details, see the article by Jura et al., pages 13545–13559.

Editorial

Editors' Picks Highlights

Editors' Picks

Accelerated Communications

Cell Biology

Developmental Biology

DNA and Chromosomes

Enzymology

Gene Regulation

Glycobiology and Extracellular Matrices

Metabolism

Microbiology

Molecular Bases of Disease

Molecular Biophysics

Neurobiology

Protein Structure and Folding

Signal Transduction

Withdrawals/Retractions

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