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August 21, 2015

Volume 290Issue 34p20629-21184
Open Access
On The Cover: G protein-coupled receptor kinases (GRKs) specifically phosphorylate activated G protein-coupled receptors. This is depicted by GRK5-mediated phosphorylation of the agonist-occupied β2-adrenergic receptor embedded in a phospholipid bilayer (original image of phospholipid bilayer was created by Skye Sawyer). A high resolution crystal structure of GRK5 is presented in the article by Komolov et al., pages 20629–20647....
On The Cover: G protein-coupled receptor kinases (GRKs) specifically phosphorylate activated G protein-coupled receptors. This is depicted by GRK5-mediated phosphorylation of the agonist-occupied β2-adrenergic receptor embedded in a phospholipid bilayer (original image of phospholipid bilayer was created by Skye Sawyer). A high resolution crystal structure of GRK5 is presented in the article by Komolov et al., pages 20629–20647.

Papers of the Week

Minireviews

Bioenergetics

Cell Biology

DNA and Chromosomes

Enzymology

Gene Regulation

Glycobiology and Extracellular Matrices

Immunology

Membrane Biology

Metabolism

Molecular Bases of Disease

Molecular Biophysics

Neurobiology

Protein Structure and Folding

Protein Synthesis and Degradation

Signal Transduction

Additions and Corrections

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