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July 16, 2010

Volume 285Issue 29p21903-22722
Open Access
On The Cover: Immunohistochemical staining of a pancreatic tissue section from a non-obese type 1 diabetic (NOD) mouse with moderate hyperglycemia (280 mg/dl). Cytokines secreted by infiltrating lymphocytes induce mixed lineage kinase-3 (MLK3) in the endocrine cells of the islet of Langerhans leading to cell death and replacement of endocrine cells with infiltrate. For details see the article by Humphrey et al., pages 22426–22436....
On The Cover: Immunohistochemical staining of a pancreatic tissue section from a non-obese type 1 diabetic (NOD) mouse with moderate hyperglycemia (280 mg/dl). Cytokines secreted by infiltrating lymphocytes induce mixed lineage kinase-3 (MLK3) in the endocrine cells of the islet of Langerhans leading to cell death and replacement of endocrine cells with infiltrate. For details see the article by Humphrey et al., pages 22426–22436.

Papers of the Week

Minireviews

Reports

Bioenergetics

Cell Biology

Computational Biology

DNA and Chromosomes

Enzymology

Gene Regulation

Genomics and Proteomics

Glycobiology and Extracellular Matrices

Immunology

Lipids

Membrane Biology

Metabolism

Microbiology

Molecular Bases of Disease

Molecular Biophysics

Neurobiology

Protein Structure and Folding

Protein Synthesis and Degradation

RNA

Signal Transduction

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