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March 09, 2012

Volume 287Issue 11p7834-8661
Open Access
On The Cover: The RNA polymerase II C-terminal domain (CTD) is subject to stage-specific phosphorylation during transcription. The resulting “CTD code” is read by factors involved in many cellular processes and is governed by the dynamic interplay between CTD kinases and phosphatases. We report the genomic position of major CTD kinases and phosphatases and identify Ssu72 as a bona fide phosphoserine 7 phosphatase. For details see the article by Zhang et al., pages 8541–8551....
On The Cover: The RNA polymerase II C-terminal domain (CTD) is subject to stage-specific phosphorylation during transcription. The resulting “CTD code” is read by factors involved in many cellular processes and is governed by the dynamic interplay between CTD kinases and phosphatases. We report the genomic position of major CTD kinases and phosphatases and identify Ssu72 as a bona fide phosphoserine 7 phosphatase. For details see the article by Zhang et al., pages 8541–8551.

Papers of the Week

Bioenergetics

Cell Biology

Developmental Biology

DNA and Chromosomes

Enzymology

Gene Regulation

Glycobiology and Extracellular Matrices

Immunology

Membrane Biology

Metabolism

Microbiology

Molecular Bases of Disease

Neurobiology

Plant Biology

Protein Structure and Folding

Protein Synthesis and Degradation

Signal Transduction

Additions and Corrections

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