January 01, 2010

Editorial Board
Published in issue: January 01, 2010
i-iii

Author Index
Published in issue: January 01, 2010
xi-xii

Reflections

From the Ribosome to the Spliceosome and Back Again
• Christine Guthrie
Published in issue: January 01, 2010
p1-12

Classics

Using Site-directed Mutagenesis to Study Carboxypeptidase A: the Work of William J. Rutter
• Nicole Kresge,
• Robert D. Simoni,
• Robert L. Hill
Published in issue: January 01, 2010
e1-e3

Accelerated Publication

Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators*
• Beth M. Stadtmueller,
• Katherine Ferrell,
• Frank G. Whitby,
• ...
• Howard Robinson,
• David G. Myszka,
• Christopher P. Hill
Published in issue: January 01, 2010
p13-17

Transcription, Chromatin, and Epigenetics

ASXL1 Represses Retinoic Acid Receptor-mediated Transcription through Associating with HP1 and LSD1*
• Sang-Wang Lee,
• Yang-Sook Cho,
• Jung-Min Na,
• ...
• Myengmo Kang,
• Eun-Joo Kim,
• Soo-Jong Um
Published in issue: January 01, 2010
p18-29

RNA Polymerase II C-terminal Heptarepeat Domain Ser-7 Phosphorylation Is Established in a Mediator-dependent Fashion*
• Stefan Boeing,
• Caroline Rigault,
• Martin Heidemann,
• Dirk Eick,
• Michael Meisterernst
Published in issue: January 01, 2010
p188-196

Oncogenic BRAF^V600E Induces Expression of Neuronal Differentiation Marker MAP2 in Melanoma Cells by Promoter Demethylation and Down-regulation of Transcription Repressor HES1*
• Nityanand Maddodi,
• Kumar M.R. Bhat,
• Sulochana Devi,
• Su-Chun Zhang,
• Vijayasaradhi Setaluri
Published in issue: January 01, 2010
p242-254

Identification of a Functional Network of Human Epigenetic Silencing Factors*
• Andrey Poleshko,
• Margret B. Einarson,
• Natalia Shalginskikh,
• ...
• Peter D. Adams,
• Anna Marie Skalka,
• Richard A. Katz
Published in issue: January 01, 2010
p422-433

Stable Chromatin Binding Prevents FoxA Acetylation, Preserving FoxA Chromatin Remodeling*
• Sarah Kohler,
• Lisa Ann Cirillo
Published in issue: January 01, 2010
p464-472

A Conserved Interaction between the SDI Domain of Bre2 and the Dpy-30 Domain of Sdc1 Is Required for Histone Methylation and Gene Expression*
• Paul F. South,
• Ian M. Fingerman,
• Douglas P. Mersman,
• Hai-Ning Du,
• Scott D. Briggs
Published in issue: January 01, 2010
p595-607

RNA: Processing and Catalysis

Recognition of Adenosine Residues by the Active Site of Poly(A)-specific Ribonuclease*
• Niklas Henriksson,
• Per Nilsson,
• Mousheng Wu,
• Haiwei Song,
• Anders Virtanen
Published in issue: January 01, 2010
p163-170

The Hinge Domain of the Cleavage Stimulation Factor Protein CstF-64 Is Essential for CstF-77 Interaction, Nuclear Localization, and Polyadenylation*^♦
• J.Andrew Hockert,
• Hsiang-Jui Yeh,
• Clinton C. MacDonald
Published in issue: January 01, 2010
p695-704

RNA-Mediated Regulation and Noncoding RNAs

NFκB p50-CCAAT/Enhancer-binding Protein β (C/EBPβ)-mediated Transcriptional Repression of MicroRNA let-7i following Microbial Infection*
• Steven P. O'Hara,
• Patrick L. Splinter,
• Gabriella B. Gajdos,
• ...
• Martin E. Fernandez-Zapico,
• Xian-Ming Chen,
• Nicholas F. LaRusso
Published in issue: January 01, 2010
p216-225

Protein Synthesis, Post-Translational Modification, and Degradation

Functional Characterization of the Kinase Activation Loop in Nucleophosmin (NPM)-Anaplastic Lymphoma Kinase (ALK) Using Tandem Affinity Purification and Liquid Chromatography-Mass Spectrometry*
• Peng Wang,
• Fang Wu,
• Yupo Ma,
• Liang Li,
• Raymond Lai,
• Leah C. Young
Published in issue: January 01, 2010
p95-103

Structure and Function of the PLAA/Ufd3-p97/Cdc48 Complex*
• Liyan Qiu,
• Natasha Pashkova,
• John R. Walker,
• ...
• Masato Akutsu,
• Robert Piper,
• Sirano Dhe-Paganon
Published in issue: January 01, 2010
p365-372

A Disintegrin and Metalloproteinase 17 (ADAM17) Mediates Inflammation-induced Shedding of Syndecan-1 and -4 by Lung Epithelial Cells*
• Jessica Pruessmeyer,
• Christian Martin,
• Franz M. Hess,
• ...
• Antonio Sechi,
• Stefan Uhlig,
• Andreas Ludwig
Published in issue: January 01, 2010
p555-564

Characterization of Alternative Isoforms and Inclusion Body of the TAR DNA-binding Protein-43*
• Yoshinori Nishimoto,
• Daisuke Ito,
• Takuya Yagi,
• Yoshihiro Nihei,
• Yoshiko Tsunoda,
• Norihiro Suzuki
Published in issue: January 01, 2010
p608-619

Src Kinase-mediated Phosphorylation Stabilizes Inducible Nitric-oxide Synthase in Normal Cells and Cancer Cells*
• Alexey Tyryshkin,
• F.Murat Gorgun,
• Elmoataz Abdel Fattah,
• ...
• Lavannya Pandit,
• Shenyan Zeng,
• N.Tony Eissa
Published in issue: January 01, 2010
p784-792

Genomics, Proteomics, and Bioinformatics

Identification and Characterization of a Novel Deoxyhypusine Synthase in Leishmania donovani*
• Bhavna Chawla,
• Anupam Jhingran,
• Sushma Singh,
• ...
• N. Srinivasan,
• Sigrid C. Roberts,
• Rentala Madhubala
Published in issue: January 01, 2010
p453-463

Protein Structure and Folding

Differential Effects of Caldesmon on the Intermediate Conformational States of Polymerizing Actin*
• Renjian Huang,
• Zenon Grabarek,
• Chih-Lueh Albert Wang
Published in issue: January 01, 2010
p71-79

Modular Control of Cross-oligomerization
ANALYSIS OF SUPERSTABILIZED Hsp90 HOMODIMERS IN VIVO *
• Natalie Wayne,
• YuShuan Lai,
• Les Pullen,
• Daniel N. Bolon
Published in issue: January 01, 2010
p234-241

C-terminal Domain Modulates the Nucleic Acid Chaperone Activity of Human T-cell Leukemia Virus Type 1 Nucleocapsid Protein via an Electrostatic Mechanism*
• Dominic F. Qualley,
• Kristen M. Stewart-Maynard,
• Fei Wang,
• ...
• Ioulia Rouzina,
• Mark C. Williams,
• Karin Musier-Forsyth
Published in issue: January 01, 2010
p295-307

Clostridium perfringens Enterotoxin Interacts with Claudins via Electrostatic Attraction*
• Jun Kimura,
• Hiroyuki Abe,
• Shigeki Kamitani,
• ...
• Yoshiko Sugita-Konishi,
• Shigeki Yamamoto,
• Yasuhiko Horiguchi
Published in issue: January 01, 2010
p401-408

Structural and Dynamic Features of the MutT Protein in the Recognition of Nucleotides with the Mutagenic 8-Oxoguanine Base*
• Teruya Nakamura,
• Sachiko Meshitsuka,
• Seiju Kitagawa,
• ...
• Satoshi Fujii,
• Mutsuo Sekiguchi,
• Yuriko Yamagata
Published in issue: January 01, 2010
p444-452

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity*
• Haina Qin,
• Roberta Noberini,
• Xuelu Huan,
• Jiahai Shi,
• Elena B. Pasquale,
• Jianxing Song
Published in issue: January 01, 2010
p644-654

Designed Auto-assembly of Nanostreptabodies for Rapid Tissue-specific Targeting in Vivo*
• Philippe Valadon,
• Bryan Darsow,
• Tim N. Buss,
• ...
• Per Borgstrom,
• Adrian Chrastina,
• Jan E. Schnitzer
Published in issue: January 01, 2010
p713-722

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor*
• Christina Rye Underwood,
• Patrick Garibay,
• Lotte Bjerre Knudsen,
• ...
• Günther H. Peters,
• Rainer Rudolph,
• Steffen Reedtz-Runge
Published in issue: January 01, 2010
p723-730

Enzyme Catalysis and Regulation

Engineering Monolignol 4-O-Methyltransferases to Modulate Lignin Biosynthesis*
• Mohammad-Wadud Bhuiya,
• Chang-Jun Liu
Published in issue: January 01, 2010
p277-285

Versatile Loops in Mycocypins Inhibit Three Protease Families*
• Miha Renko,
• Jerica Sabotič,
• Marko Mihelič,
• Jože Brzin,
• Janko Kos,
• Dušan Turk
Published in issue: January 01, 2010
p308-316

Regulated Cleavage of Prothrombin by Prothrombinase
REPOSITIONING A CLEAVAGE SITE REVEALS THE UNIQUE KINETIC BEHAVIOR OF THE ACTION OF PROTHROMBINASE ON ITS COMPOUND SUBSTRATE *^♦
• Harlan N. Bradford,
• Joseph A. Micucci,
• Sriram Krishnaswamy
Published in issue: January 01, 2010
p328-338

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism*
• Nathan A. Lack,
• Katherine C. Yam,
• Edward D. Lowe,
• ...
• Robin L. Owen,
• Edith Sim,
• Lindsay D. Eltis
Published in issue: January 01, 2010
p434-443

YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity*
• Feng Rao,
• Rui Yin See,
• Dongwei Zhang,
• Delon Chengxu Toh,
• Qiang Ji,
• Zhao-Xun Liang
Published in issue: January 01, 2010
p473-482

Transcriptional Co-activator LEDGF Interacts with Cdc7-Activator of S-phase Kinase (ASK) and Stimulates Its Enzymatic Activity*
• Siobhan Hughes,
• Victoria Jenkins,
• Mohd Jamal Dar,
• Alan Engelman,
• Peter Cherepanov
Published in issue: January 01, 2010
p541-554

Adaptive Modifications in the Calpain/Calpastatin System in Brain Cells after Persistent Alteration in Ca²⁺ Homeostasis*
• Roberto Stifanese,
• Monica Averna,
• Roberta De Tullio,
• ...
• Giambattista Bonanno,
• Sandro Pontremoli,
• Edon Melloni
Published in issue: January 01, 2010
p631-643

IcmF Is a Fusion between the Radical B₁₂ Enzyme Isobutyryl-CoA Mutase and Its G-protein Chaperone*
• Valentin Cracan,
• Dominique Padovani,
• Ruma Banerjee
Published in issue: January 01, 2010
p655-666

Metabolism and Bioenergetics

AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance*
• Nicolas Dzamko,
• Bryce J.W. van Denderen,
• Andrea L. Hevener,
• ...
• Duncan J. Campbell,
• Gregory R. Steinberg,
• Bruce E. Kemp
Published in issue: January 01, 2010
p115-122

Direct Evidence for Nitrogen Ligation to the High Stability Semiquinone Intermediate in Escherichia coli Nitrate Reductase A*
• Stéphane Grimaldi,
• Rodrigo Arias-Cartin,
• Pascal Lanciano,
• ...
• Thomas F. Prisner,
• Axel Magalon,
• Bruno Guigliarelli
Published in issue: January 01, 2010
p179-187

Branched-chain Amino Acid Metabolon
INTERACTION OF GLUTAMATE DEHYDROGENASE WITH THE MITOCHONDRIAL BRANCHED-CHAIN AMINOTRANSFERASE (BCATm) *
• Mohammad Mainul Islam,
• Manisha Nautiyal,
• R.Max Wynn,
• James A. Mobley,
• David T. Chuang,
• Susan M. Hutson
Published in issue: January 01, 2010
p265-276

Calcium-activated Calpain-2 Is a Mediator of Beta Cell Dysfunction and Apoptosis in Type 2 Diabetes*
• Chang-jiang Huang,
• Tatyana Gurlo,
• Leena Haataja,
• ...
• Xiuji Wu,
• Alexandra E. Butler,
• Peter C. Butler
Published in issue: January 01, 2010
p339-348

Heme-binding Protein HRG-1 Is Induced by Insulin-like Growth Factor I and Associates with the Vacuolar H⁺-ATPase to Control Endosomal pH and Receptor Trafficking*
• Katie M. O'Callaghan,
• Veronica Ayllon,
• Jean O'Keeffe,
• ...
• Gary Loughran,
• Michael Forgac,
• Rosemary O'Connor
Published in issue: January 01, 2010
p381-391

Direct Demonstration of Half-of-the-sites Reactivity in the Dimeric Cytochrome bc₁ Complex
ENZYME WITH ONE INACTIVE MONOMER IS FULLY ACTIVE BUT UNABLE TO ACTIVATE THE SECOND UBIQUINOL OXIDATION SITE IN RESPONSE TO LIGAND BINDING AT THE UBIQUINONE REDUCTION SITE *
• Michela Castellani,
• Raul Covian,
• Thomas Kleinschroth,
• Oliver Anderka,
• Bernd Ludwig,
• Bernard L. Trumpower
Published in issue: January 01, 2010
p502-510

Thiamine Triphosphate Synthesis in Rat Brain Occurs in Mitochondria and Is Coupled to the Respiratory Chain*
• Marjorie Gangolf,
• Pierre Wins,
• Marc Thiry,
• Benaïssa El Moualij,
• Lucien Bettendorff
Published in issue: January 01, 2010
p583-594

Subunit Organization and Reversal-associated Movements in the Flagellar Switch of Escherichia coli*^♦
• Mayukh K. Sarkar,
• Koushik Paul,
• David F. Blair
Published in issue: January 01, 2010
p675-684

Increased Potassium Conductance of Brain Mitochondria Induces Resistance to Permeability Transition by Enhancing Matrix Volume*
• Magnus J. Hansson,
• Saori Morota,
• Maria Teilum,
• Gustav Mattiasson,
• Hiroyuki Uchino,
• Eskil Elmér
Published in issue: January 01, 2010
p741-750

Glycobiology and Extracellular Matrices

Cell-surface Processing of the Metalloprotease Pro-ADAMTS9 Is Influenced by the Chaperone GRP94/gp96*
• Bon-Hun Koo,
• Suneel S. Apte
Published in issue: January 01, 2010
p197-205

Regulation of Phagocytosis in Macrophages by Neuraminidase 1*
• Volkan Seyrantepe,
• Alexandre Iannello,
• Feng Liang,
• ...
• Myron R. Szewczuk,
• Ali Ahmad,
• Alexey V. Pshezhetsky
Published in issue: January 01, 2010
p206-215

Characterization of a Bifunctional Pyranose-Furanose Mutase from Campylobacter jejuni 11168*
• Myles B. Poulin,
• Harald Nothaft,
• Isabelle Hug,
• Mario F. Feldman,
• Christine M. Szymanski,
• Todd L. Lowary
Published in issue: January 01, 2010
p493-501

Efficient Glycosynthase Mutant Derived from Mucor hiemalis Endo-β-N-acetylglucosaminidase Capable of Transferring Oligosaccharide from Both Sugar Oxazoline and Natural N-Glycan*
• Midori Umekawa,
• Cishan Li,
• Takayuki Higashiyama,
• ...
• Hisashi Ashida,
• Kenji Yamamoto,
• Lai-Xi Wang
Published in issue: January 01, 2010
p511-521

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Heparan Sulfate 2-O-Sulfotransferase Is Required for Triglyceride-rich Lipoprotein Clearance*
• Kristin I. Stanford,
• Lianchun Wang,
• Jan Castagnola,
• ...
• Wellington V. Cardoso,
• Koji Kimata,
• Jeffrey D. Esko
Published in issue: January 01, 2010
p286-294

Secretory Phospholipase A₂, Group IIA Is a Novel Serum Amyloid A Target Gene
ACTIVATION OF SMOOTH MUSCLE CELL EXPRESSION BY AN INTERLEUKIN-1 RECEPTOR-INDEPENDENT MECHANISM *
• Christopher P. Sullivan,
• Stephanie E. Seidl,
• Celeste B. Rich,
• Michel Raymondjean,
• Barbara M. Schreiber
Published in issue: January 01, 2010
p565-575

Substrate Efflux Propensity Plays a Key Role in the Specificity of Secretory A-type Phospholipases*
• Perttu Haimi,
• Martin Hermansson,
• Krishna Chaithanya Batchu,
• Jorma A. Virtanen,
• Pentti Somerharju
Published in issue: January 01, 2010
p751-760

Membrane Transport, Structure, Function, and Biogenesis

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling*
• Mark P. Jedrychowski,
• Carlos A. Gartner,
• Steven P. Gygi,
• ...
• Joachim Herz,
• Konstantin V. Kandror,
• Paul F. Pilch
Published in issue: January 01, 2010
p104-114

Determination of the Dissociation Constants for Ca²⁺ and Calmodulin from the Plasma Membrane Ca²⁺ Pump by a Lipid Probe That Senses Membrane Domain Changes*
• Irene Mangialavori,
• Mariela Ferreira-Gomes,
• María F. Pignataro,
• Emanuel E. Strehler,
• Juan Pablo F.C. Rossi
Published in issue: January 01, 2010
p123-130

Functional Analysis of the Kv1.1 N255D Mutation Associated with Autosomal Dominant Hypomagnesemia*
• Jenny van der Wijst,
• Bob Glaudemans,
• Hanka Venselaar,
• ...
• Anna-Lena Forst,
• Joost G.J. Hoenderop,
• René J.M. Bindels
Published in issue: January 01, 2010
p171-178

Bordetella Adenylate Cyclase Toxin Promotes Calcium Entry into Both CD11b⁺ and CD11b⁻ Cells through cAMP-dependent L-type-like Calcium Channels*
• César Martín,
• Geraxane Gómez-Bilbao,
• Helena Ostolaza
Published in issue: January 01, 2010
p357-364

Molecular Basis of the Potent Membrane-remodeling Activity of the Epsin 1 N-terminal Homology Domain*
• Youngdae Yoon,
• Jiansong Tong,
• Park Joo Lee,
• ...
• Enrico Gratton,
• Yeon-Kyun Shin,
• Wonhwa Cho
Published in issue: January 01, 2010
p531-540

Identification and Characterization of Unique Proline-rich Peptides Binding to the Mitochondrial Fission Protein hFis1*
• Madhavika N. Serasinghe,
• A.M.P.B. Seneviratne,
• Alan V. Smrcka,
• Yisang Yoon
Published in issue: January 01, 2010
p620-630

Dissecting the N-Ethylmaleimide-sensitive Factor
REQUIRED ELEMENTS OF THE N AND D1 DOMAINS *
• Chunxia Zhao,
• Elena A. Matveeva,
• Qiansheng Ren,
• Sidney W. Whiteheart
Published in issue: January 01, 2010
p761-772

Molecular Basis of Cell and Developmental Biology

Wnt/β-Catenin and Retinoic Acid Receptor Signaling Pathways Interact to Regulate Chondrocyte Function and Matrix Turnover*
• Rika Yasuhara,
• Takahito Yuasa,
• Julie A. Williams,
• ...
• Maurizio Pacifici,
• Masahiro Iwamoto,
• Motomi Enomoto-Iwamoto
Published in issue: January 01, 2010
p317-327

Chaperokine Function of Recombinant Hsp72 Produced in Insect Cells Using a Baculovirus Expression System Is Retained*
• Hongying Zheng,
• Ganachari M. Nagaraja,
• Punit Kaur,
• Edwina E. Asea,
• Alexzander Asea
Published in issue: January 01, 2010
p349-356

Ptf1a Directly Controls Expression of Immunoglobulin Superfamily Molecules Nephrin and Neph3 in the Developing Central Nervous System*
• Kazuhiko Nishida,
• Mikio Hoshino,
• Yoshiya Kawaguchi,
• Fujio Murakami
Published in issue: January 01, 2010
p373-380

β-Catenin Up-regulates Atoh1 Expression in Neural Progenitor Cells by Interaction with an Atoh1 3′ Enhancer*
• Fuxin Shi,
• Yen-fu Cheng,
• Xiaohui L. Wang,
• Albert S.B. Edge
Published in issue: January 01, 2010
p392-400

Constitutive Reactive Oxygen Species Generation from Autophagosome/Lysosome in Neuronal Oxidative Toxicity*
• Chisato Kubota,
• Seiji Torii,
• Ni Hou,
• ...
• Yuhei Yoshimoto,
• Hideaki Imai,
• Toshiyuki Takeuchi
Published in issue: January 01, 2010
p667-674

Misfolded Proinsulin Affects Bystander Proinsulin in Neonatal Diabetes*
• Israel Hodish,
• Ming Liu,
• Gautam Rajpal,
• ...
• Aaron Adams,
• Leanza Liu,
• Peter Arvan
Published in issue: January 01, 2010
p685-694

Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of a GATA1 Protein Lacking the N-terminal Domain*
• Eri Kobayashi,
• Ritsuko Shimizu,
• Yuko Kikuchi,
• Satoru Takahashi,
• Masayuki Yamamoto
Published in issue: January 01, 2010
p773-783

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death*
• Satoru Kobayashi,
• Paul Volden,
• Derek Timm,
• Kai Mao,
• Xianmin Xu,
• Qiangrong Liang
Published in issue: January 01, 2010
p793-804

Mechanisms of Signal Transduction

Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by α_vβ₃ and β₁ Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway*
• Ding-Yu Lee,
• Yi-Shuan J. Li,
• Shun-Fu Chang,
• ...
• Hui-Min Ho,
• Jeng-Jiann Chiu,
• Shu Chien
Published in issue: January 01, 2010
p30-42

Roscovitine Binds to Novel L-channel (Ca_V1.2) Sites That Separately Affect Activation and Inactivation*
• Viktor Yarotskyy,
• Guofeng Gao,
• Lei Du,
• Sindura B. Ganapathi,
• Blaise Z. Peterson,
• Keith S. Elmslie
Published in issue: January 01, 2010
p43-53

Serine-Threonine Kinase Receptor-associated Protein Inhibits Apoptosis Signal-regulating Kinase 1 Function through Direct Interaction*
• Haiyoung Jung,
• Hyun-A Seong,
• Ravi Manoharan,
• Hyunjung Ha
Published in issue: January 01, 2010
p54-70

Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser⁸⁶³ and Multisite Phosphorylation*
• Kathryn G. Foster,
• Hugo A. Acosta-Jaquez,
• Yves Romeo,
• ...
• Philippe P. Roux,
• Bryan A. Ballif,
• Diane C. Fingar
Published in issue: January 01, 2010
p80-94

α5β1 Integrin Engagement Increases Large Conductance, Ca²⁺-activated K⁺ Channel Current and Ca²⁺ Sensitivity through c-src-mediated Channel Phosphorylation*
• Yan Yang,
• Xin Wu,
• Peichun Gui,
• ...
• Andrew P. Braun,
• George E. Davis,
• Michael J. Davis
Published in issue: January 01, 2010
p131-141

Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression*
• Winyoo Chowanadisai,
• Kathryn A. Bauerly,
• Eskouhie Tchaparian,
• Alice Wong,
• Gino A. Cortopassi,
• Robert B. Rucker
Published in issue: January 01, 2010
p142-152

Antioxidant-induced Phosphorylation of Tyrosine 486 Leads to Rapid Nuclear Export of Bach1 That Allows Nrf2 to Bind to the Antioxidant Response Element and Activate Defensive Gene Expression*
• James W. Kaspar,
• Anil K. Jaiswal
Published in issue: January 01, 2010
p153-162

Claudin-1 Acts through c-Abl-Protein Kinase Cδ (PKCδ) Signaling and Has a Causal Role in the Acquisition of Invasive Capacity in Human Liver Cells*
• Chang-Hwan Yoon,
• Min-Jung Kim,
• Myung-Jin Park,
• ...
• Yung-Hyun Choi,
• Gyesoon Yoon,
• Su-Jae Lee
Published in issue: January 01, 2010
p226-233

HECT Domain-containing E3 Ubiquitin Ligase Nedd4 Interacts with and Ubiquitinates Sprouty2*
• Francis Edwin,
• Kimberly Anderson,
• Tarun B. Patel
Published in issue: January 01, 2010
p255-264

Increased cAMP Levels Modulate Transforming Growth Factor-β/Smad-induced Expression of Extracellular Matrix Components and Other Key Fibroblast Effector Functions
• Meinhard Schiller,
• Sylviane Dennler,
• Ulf Anderegg,
• ...
• Thomas A. Luger,
• Alain Mauviel,
• Markus Böhm
Published in issue: January 01, 2010
p409-421

Translocation of Sphingosine Kinase 1 to the Plasma Membrane Is Mediated by Calcium- and Integrin-binding Protein 1*
• Kate E. Jarman,
• Paul A.B. Moretti,
• Julia R. Zebol,
• Stuart M. Pitson
Published in issue: January 01, 2010
p483-492

B-cell CLL/Lymphoma 10 (BCL10) Is Required for NF-κB Production by Both Canonical and Noncanonical Pathways and for NF-κB-inducing Kinase (NIK) Phosphorylation*
• Sumit Bhattacharyya,
• Alip Borthakur,
• Sangeeta Tyagi,
• ...
• Mei Ling Chen,
• Pradeep K. Dudeja,
• Joanne K. Tobacman
Published in issue: January 01, 2010
p522-530

CD38-mediated Ca²⁺ Signaling Contributes to Angiotensin II-induced Activation of Hepatic Stellate Cells
ATTENUATION OF HEPATIC FIBROSIS BY CD38 ABLATION *
• Seon-Young Kim,
• Baik Hwan Cho,
• Uh-Hyun Kim
Published in issue: January 01, 2010
p576-582

Hyperactive Intracellular Calcium Signaling Associated with Localized Mitochondrial Defects in Skeletal Muscle of an Animal Model of Amyotrophic Lateral Sclerosis*
• Jingsong Zhou,
• Jianxun Yi,
• Ronggen Fu,
• ...
• Teepu Siddique,
• Eduardo Ríos,
• Han-Xiang Deng
Published in issue: January 01, 2010
p705-712

Differential Regulation of TRPV1, TRPV3, and TRPV4 Sensitivity through a Conserved Binding Site on the Ankyrin Repeat Domain*
• Christopher B. Phelps,
• Ruiqi R. Wang,
• Shelly S. Choo,
• Rachelle Gaudet
Published in issue: January 01, 2010
p731-740

Prothrombin Docking Maneuvers♦
Regulated Cleavage of Prothrombin by Prothrombinase. Repositioning a Cleavage Site Reveals the Unique Kinetic Behavior of the Action of Prothrombinase on Its Compound Substrate
Published in issue: January 01, 2010
e99901

Flagellar Organization♦
Subunit Organization and Reversal-associated Movements in the Flagellar Switch of Escherichia coli
Published in issue: January 01, 2010
e99902

mRNA Processing Gets a SLAP♦
The Hinge Domain of the Cleavage Stimulation Factor Protein CstF-64 Is Essential for CstF-77 Interaction, Nuclear Localization, and Polyadenylation
Published in issue: January 01, 2010
e99903