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February 20, 2009

Volume 284Issue 8p4749-e99905
Open Access
On The Cover: Embryonal carcinoma P19 cells express a pluripotent transcription factor Oct3/4 and can differentiate into either neural or myogenic cells, in response to the distinct stimuli and culture conditions. Epifluorescence images show neuronal cell morphology of the retinoic acid-induced differentiated P19 cells. A small GTPase Cdc42 influences neural progenitor cell fate by regulating gene expression in P19 cells. For details see the article by Endo et al., pages 5107–5118....
On The Cover: Embryonal carcinoma P19 cells express a pluripotent transcription factor Oct3/4 and can differentiate into either neural or myogenic cells, in response to the distinct stimuli and culture conditions. Epifluorescence images show neuronal cell morphology of the retinoic acid-induced differentiated P19 cells. A small GTPase Cdc42 influences neural progenitor cell fate by regulating gene expression in P19 cells. For details see the article by Endo et al., pages 5107–5118.

Minireviews

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Transcription, Chromatin, and Epigenetics

RNA: Processing and Catalysis

RNA-Mediated Regulation and Noncoding RNAs

Protein Synthesis, Post-Translational Modification, and Degradation

Protein Structure and Folding

Enzyme Catalysis and Regulation

Metabolism and Bioenergetics

Glycobiology and Extracellular Matrices

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Membrane Transport, Structure, Function, and Biogenesis

Molecular Basis of Cell and Developmental Biology

Mechanisms of Signal Transduction

Papers of the Week

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