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April 24, 2009

Volume 284Issue 17p10993-11748
Open Access
On The Cover: Crystal structure of the preQ1 riboswitch aptamer domain (transparent surface) from Thermoanaerobacter tengcongensis. The RNA backbone is depicted as a purple tube with associated bases colored according to position from the 5′-end (blue) to the 3′-end (red). Free and bound metabolite molecules are depicted as ball-and-stick models with transparent surfaces (pink). (Graphic by J. E. Wedekind.) For details see the article by Spitale et al., pages 11012–11016....
On The Cover: Crystal structure of the preQ1 riboswitch aptamer domain (transparent surface) from Thermoanaerobacter tengcongensis. The RNA backbone is depicted as a purple tube with associated bases colored according to position from the 5′-end (blue) to the 3′-end (red). Free and bound metabolite molecules are depicted as ball-and-stick models with transparent surfaces (pink). (Graphic by J. E. Wedekind.) For details see the article by Spitale et al., pages 11012–11016.

Thematic Minireview Series

Accelerated Publication

DNA: Replication, Repair, Recombination, and Chromosome Dynamics

Transcription, Chromatin, and Epigenetics

RNA: Processing and Catalysis

RNA-Mediated Regulation and Noncoding RNAS

Protein Synthesis, Post-Translational Modification, and Degradation

Protein Structure and Folding

Enzyme Catalysis and Regulation

Metabolism and Bioenergetics

Glycobiology and Extracellular Matrices

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling

Membrane Transport, Structure, Function, and Biogenesis

Molecular Basis of Cell and Developmental Biology

Mechanisms of Signal Transduction

Biomolecular Networks

Additions and Corrections

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