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November 2021

Volume 297Issue 5
Open Access
On the Cover: SARS-CoV-2 variants are evolving by maximizing the biophysical fitness parameters, in particular increased affinity of spike protein (receptor binding domain red colored) to ACE2 receptor (blue colored), escape from neutralizing antibodies (antigen binding fragment green colored), increased protein expression, and at the same time maintaining protein stability despite the nonconservative nature of mutations. For details, see the article by Upadhyay et al., 101208....
On the Cover: SARS-CoV-2 variants are evolving by maximizing the biophysical fitness parameters, in particular increased affinity of spike protein (receptor binding domain red colored) to ACE2 receptor (blue colored), escape from neutralizing antibodies (antigen binding fragment green colored), increased protein expression, and at the same time maintaining protein stability despite the nonconservative nature of mutations. For details, see the article by Upadhyay et al., 101208.
  • Cover

    Published in issue: November 2021
    101488

Editorial

Editors’ Picks Highlight

JBC Reviews

Reflections

Accelerated Communication

Methods and Resources

Classics

Letters to the Editor

Meeting Report

Cell Biology

Computational Biology

DNA and Chromosomes

Enzymology

Gene Regulation

Genomics and Proteomics

Glycobiology and Extracellular Matrices

Immunology

Lipids

Metabolism

Methods

Microbiology

Molecular Bases of Disease

Molecular Biophysics

Neurobiology

Plant Biology

Protein Structure and Folding

Protein Synthesis and Degradation

RNA

Signal Transduction

Additions and Corrections

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