x
Filter:
Filters applied
- Accelerated Communications
- Asthana, ShailendraRemove Asthana, Shailendra filter
Publication Date
Please choose a date range between 2020 and 2020.
JBC Communications
1 Results
- Accelerated CommunicationsOpen Access
Identification of an anti–SARS–CoV-2 receptor-binding domain–directed human monoclonal antibody from a naïve semisynthetic library
Journal of Biological ChemistryVol. 295Issue 36p12814–12821Published online: July 29, 2020- Hilal Ahmad Parray
- Adarsh Kumar Chiranjivi
- Shailendra Asthana
- Naveen Yadav
- Tripti Shrivastava
- Shailendra Mani
- and others
Cited in Scopus: 42There is a desperate need for safe and effective vaccines, therapies, and diagnostics for SARS– coronavirus 2 (CoV-2), the development of which will be aided by the discovery of potent and selective antibodies against relevant viral epitopes. Human phage display technology has revolutionized the process of identifying and optimizing antibodies, providing facile entry points for further applications. Herein, we use this technology to search for antibodies targeting the receptor-binding domain (RBD) of CoV-2.