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JBC Communications
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- Accelerated CommunicationOpen Access
Potent mouse monoclonal antibodies that block SARS-CoV-2 infection
Journal of Biological ChemistryVol. 296100346Published online: January 29, 2021- Youjia Guo
- Atsushi Kawaguchi
- Masaru Takeshita
- Takeshi Sekiya
- Mikako Hirohama
- Akio Yamashita
- and others
Cited in Scopus: 9Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has developed into a global pandemic since its first outbreak in the winter of 2019. An extensive investigation of SARS-CoV-2 is critical for disease control. Various recombinant monoclonal antibodies of human origin that neutralize SARS-CoV-2 infection have been isolated from convalescent patients and will be applied as therapies and prophylaxis. However, the need for dedicated monoclonal antibodies suitable for molecular pathology research is not fully addressed.