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    Open Access

    Glycolysis and gluconeogenesis: A teaching view

    Journal of Biological Chemistry
    Vol. 296100016Published online: December 7, 2020
    • Félix Hernández
    Cited in Scopus: 0
      I read with interest the recent review “Tracking the carbons supplying gluconeogenesis” by Ankit M. Shah and Fredric E. Wondisford (1). The figures are clear, and they are a good teaching source. Nevertheless, I note some potential teaching issues as well as offer additional suggestions. It is well known and it is explained to our students that there are three reactions of glycolysis that are essentially irreversible: hexokinase, phosphofrutokinase-1, and pyruvate kinase. Thus, I would like to observe in relation to Figure 1 that

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