- The truth of a theory lies in the deductive methods used to establish it and the experimental demonstration of its fundamental premises and consequences—Jacques Monod
- For the past fifty-five years, much of my research has focused on the function and biogenesis of red blood cells, including the cloning and study of many membrane proteins such as glucose and anion transporters and the erythropoietin receptor. We have also elucidated the mechanisms of membrane insertion, folding, and maturation of many plasma membrane and secreted proteins. Despite all of this work and more, I remain extremely proud of our very early work on the regulation of mRNA translation: work on bacteriophage f2 RNA in the 1960s and on translation of α- and β-globin mRNAs in the early 1970s.
- Having been offered the opportunity to contribute one of the episodes of this series of personal history accounts, I have chosen to write about circumstances that led me to the start of the scientific path that I have followed for the past forty odd years. My account deals with a period of approximately six years and with events that I have written about recently (1); although I have been conscientious about avoiding overt self-plagiarism (at least the kind that is detected by computer programs), I also hope to have added some additional perspective.