In reflecting on the past 80 years, at least as they have affected me, it seems that fate (or nature or God, take your choice) has dealt me an unusually good hand. For example, my father and brother both had serious coronary heart attacks in their early 50s. While I was developing the same blocked arteries, methods were being devised to treat the condition with stents and statins. Much of my good fortune has been dumb luck like this, simply being in the right place at the right time. I know it is hyperbole, but growing up in the fields of biochemistry and biology has been a little like growing up as a musician in 18th century and early 19th century Vienna.