Virtual Issues

Virtual issues are collections of recently published JBC papers in a particular field. These issues are created by the JBC editorial team to highlight a topic that has attracted significant publications in JBC. We welcome your suggestions for future topical collections.

Cover thumbnail for Virtual issue: RNA polymerase II and transcriptional regulation

Virtual issue: RNA polymerase II and transcriptional regulation

In this virtual issue, we highlight ten articles on RNA polymerase II and transcriptional regulation recently published in the Journal of Biological Chemistry to celebrate this crucial field of research.

Assembled by Alex Toker and Chengmin Jiang

Published September 2022

Cover thumbnail for Virtual issue: Epigenetic regulation in JBC

Virtual issue: Epigenetic regulation in JBC

In this virtual issue, we highlight ten articles on epigenetic regulation recently published in the Journal of Biological Chemistry to celebrate the scientific advancement in this important and trending field.

Assembled by Alex Toker and Chengmin Jiang

Published September 2022

Cover thumbnail for Virtual issue: Focus on Europe

Virtual issue: Focus on Europe

In the recent decades, scientists from European countries have been contributing highly impactful research in The Journal of Biological Chemistry (JBC). This Virtual Issue highlights 14 research articles from Europe to celebrate the many exciting scientific advances and new insights in biochemistry and molecular biology by these scientists.

Assembled by Alex Toker and Chengmin Jiang

Published June 2022

Cover thumbnail for Virtual issue: Focus on China

Virtual issue: Focus on China

Throughout the years, researchers from China have been contributing a significant amount of work in The Journal of Biological Chemistry (JBC). This Virtual Issue showcases just a small fraction of the many exciting scientific advances and new insights in biochemistry and molecular biology made by scientists in the People’s Republic of China in recent years.

Assembled by Alex Toker and Chengmin Jiang

Published May 2022

Virtual issue: ESCRT biology in JBC

Virtual issue: ESCRT biology in JBC

In this virtual issue, we highlight nine articles on the endosomal sorting complex required for transport (ESCRT), recently published in the Journal of Biological Chemistry to celebrate this exciting and evolving field.

Assembled by Chengmin Jiang

Published April 2022

Cover thumbnail for Virtual issue: Methods Madness: 2022

Virtual issue: Methods Madness: 2022

These are the highlighted articles from the Final Four 2022 JBC Methods Madness tournament - mass spectrometry, cryo–EM/ET, CRISPR and advanced chromatography.

Published April 2022

The year in JBC: 2021

The year in JBC: 2021

This issue celebrates a few of the new insights, advances and tools that moved scientific research forward in 2021.

Assembled by Alex Toker (Editor-in-Chief) and Fred Guengerich (Deputy Editor)

Published December 2021

Cover thumbnail for Virtual Issue: JBC and JLR: 100 Years of the Discovery of Insulin

Virtual issue: JBC and JLR: 100 years since the discovery of insulin

In this joint virtual issue, we have selected 27 articles published in the Journal of Biological Chemistry and Journal of Lipid Research over the past century to celebrate the 100th anniversary since the discovery of insulin and the research triumphs that followed.

Assembled by Alan D. Attie, Qi-Qun Tang and Karin E. Bornfeldt

Published November 2021

Cover thumbnail for Virtual issue: Methods Madness: 2021

Virtual issue: Methods Madness: 2021

This virtual issue highlights some of the scientific advances and insights made using mass spectrometry, cryo–EM/ET, x-ray crystallography and live-cell imaging — influential scientific methodologies that were the final four competitors in the 2021 JBC Methods Madness tournament.

Assembled by Anand Rao

Published April 2021

Cover thumbnail for Virtual Issue: The PDB in JBC

The PDB in JBC

In this issue, we celebrate the PDB’s 50th anniversary by offering you a collection of some of the seminal structures published in JBC over the last 50 years.

Assembled by Lila Gierasch and Helen Berman

Published March 2021

Year in 2020

The year in JBC: 2020

This issue, featuring articles from volume 295, celebrates a few of the new insights, advances and tools that moved scientific research forward in 2020.

Assembled by the editors of JBC

Published January 2021

Cover thumbnail for JBC The eukaryotic cytoskeleton issue

The eukaryotic cytoskeleton

In this issue, explore the polymers and motor proteins that determine the function of the eukaryotic cytoskeleton in cell migration, cardiac health, neurodegeneration, and more.

Assembled by Enrique M. De La Cruz

Published September 2020

Women in biological chemistry

Women in biological chemistry

In this issue, we celebrate outstanding work by women scientists and call for further progress a century after the adoption of the 19th Amendment.

Assembled by Catherine Goodman and Karen Fleming

Published August 2020

Coronaviruses

Coronaviruses

This issue presents a collection of content on coronavirus entry, proteases, and host interactions to help researchers build more quickly toward therapeutic endpoints against SARS-CoV-2 and future strains.

Assembled by Craig Cameron

Published February 2020; updated July 2020

The microbiome

The microbiome

In this issue, dive into the diverse chemicals, chemical reactions, and interspecies crosstalk that are found in the gut.

Assembled by Chris Whitfield

Published June 2020

Methods Madness

Methods Madness

This virtual issue highlights the scientific advances and insights made using cryo–EM/ET, CRISPR, mass spectrometry and PCR/molecular cloning — influential scientific methodologies that were part of the inaugural JBC Methods Madness tournament.

Assembled by Anand Rao

Published May 2020

An annual meeting in absentia

An annual meeting in absentia

This issue captures some of the scientific advances and insights we might have heard about from honored awardees, rising stars, and everyone in between at the cancelled 2020 ASBMB Annual Meeting.

Assembled by Catherine Goodman and Anand Rao

Published April 2020

Antibody engineering

Antibody engineering

In this issue, dive into the world of therapeutic antibodies with new antibody constructs, novel tools and approaches, and new ways to modify effector functions.

Assembled by Peter Cresswell

Published March 2020

Highlights of 2019

The year in JBC: 2019

This issue, featuring articles from volume 294, celebrates some of the new insights, advances and tools that have changed the face of scientific research in 2019.

Assembled by the editors of JBC

Published January 2020

Cancer

Cancer

This issue captures new discoveries on the mechanistic basis of cancer cell signaling, reprogramming of tumor metabolism, cancer genetics and the tumor microenvironment, and the development and characterization of drugs for cancer treatment.

Assembled by Alex Toker

Published December 2019

ASBMB Award Articles: The 2019 class

This issue captures the scientific advances and personal journeys of the 2019 ASBMB award winners.

Assembled by the editors of JBC

Initially published October 2019; completed November 2019

Diabetes, obesity and the metabolic syndrome

Diabetes, obesity and the metabolic syndrome

In this issue, explore the molecular regulation of adipocyte and liver metabolism as well as the cellular, tissue and whole body integration of carbohydrate metabolism and energy balance.

Assembled by Jeffrey Pessin

Published September 2019

Antibiotic activities and mechanisms of resistance

Antibiotic activities and mechanisms of resistance

This virtual issue investigates how antibiotics work and how bacteria fight back, and highlights known and new therapeutic targets that could help to combat the urgent threat of resistance.

Assembled by Chris Whitfield

Published August 2019

Extracellular vesicles

Extracellular vesicles

In this virtual issue, explore the formation, contents, and functions of these important but still mysterious mediators of cell-cell communication.

Assembled by Phyllis Hanson

Published June 2019

Focus on South America

Focus on South America

This issue showcases outstanding recent work from researchers in South America in honor of the Brazilian Society of Biochemistry and Molecular Biology’s annual meeting.

Assembled by Catherine Goodman

Published May 2019

Pluripotency regulation and differentiation

Pluripotency regulation and differentiation

This issue captures recent advances in acquiring and maintaining pluripotency and regulating differentiation.

Assembled by Xiao-Fan Wang

Published April 2019

Virtual Issue: Immunometabolism

Immunometabolism

In this virtual issue, explore the burgeoning area of immunometabolism research, which aims to define the involvement of cellular metabolism in regulating immune cell functions such as differentiation, innate immunity and inflammatory responses.

Assembled by Luke O’Neill

Published March 2019

ASBMB award winners in the spotlight

ASBMB award winners in the spotlight

This issue captures the scientific advances and personal journeys of the 2018 ASBMB award winners.

Assembled by the editors of JBC

Initially published July 2018; completed February 2019

Highlights of 2018

The year in JBC: 2018

This issue presents articles published in volume 293 that are emblematic of the outstanding discoveries across JBC’s scientific scope.

Assembled by the editors of JBC

Published January 2019

Drug metabolism, transport and toxicity

Drug metabolism, transport and toxicity

This issue features enzymes that degrade or activate drug molecules, the often deleterious consequences of these catabolic reactions, and the transporters and regulatory mechanisms that define this complex metabolism.

Assembled by F. Peter Guengerich

Published September 2018

Genome editing

Genome editing

This issue highlights methodological advances and mechanistic insights in genome editing as well as the applications of these techniques for screens, the development of transgenic animals and other studies.

Assembled by Joel Gottesfeld and Catherine Goodman

Published September 2018

Omics of lipids, glycans and polar metabolites

Omics of lipids, glycans and polar metabolites

This collaborative issue, featuring papers from JBC, JLR and MCP, explores recent advances in omics research beyond proteins and nucleic acids.

Assembled by Edward A. Dennis, Gerald Hart and Catherine Goodman

Published June 2018

Signaling through space and time

Signaling through space and time

This issue highlights recent advances defining the biomolecules involved in G protein signaling and the outcomes of these signaling networks in four dimensions.

Assembled by Henrik Dohlman

Published May 2018

Amyloids, prions and protein oligomers

Amyloids, prions and protein oligomers

This issue highlights recent insights into the structure and aggregation pathways of amyloid and amyloid-like proteins in health and disease.

Assembled by Paul Fraser and Catherine Goodman

Published March 2018

Focus on Australasia

Focus on Australasia

This issue showcases outstanding recent work from researchers in Australia and New Zealand in honor of the Lorne Conference on Protein Structure and Function.

Assembled by Catherine Goodman

Published February 2018

Highlights of 2017

The year in JBC: 2017

This issue presents articles selected from each of our topical subdisciplines that showcase some of the outstanding science published in JBC in the past year.

Assembled by the editors of JBC

Published January 2018

Structural biology

Virtual issue: Structural biology

This issue captures new scientific insights made possible by the rapidly expanding structural biology capabilities that are providing new insights into all areas of biology.

Assembled by Norma Allewell, Wolfgang Peti and Catherine Goodman

Published June 2017

Highlights of 2016

Highlights of 2016

This issue presents our “Highlights of 2016” – articles selected from each of our topical subdisciplines that showcase some of the compelling science published at JBC in the past year.

Assembled by the editors of JBC

Published February 2017

Focus on China

Focus on China

This issue pays tribute to the theme of “Integrative Biochemistry”, at the heart of this year’s international conference of the Chinese Society of Biochemistry and Molecular Biology.

Assembled by Catherine Goodman and Martin Spiering

Published October 2016

Best of 2015

Best of 2015

This issue announces the “Best of the Year” articles of 2015, selected from Papers of the Week.

Assembled by the editors of JBC

Published January 2016

Best of 2014

Best of 2014

This issue announces the “Best of the Year” articles of 2014, selected to represent each of the broad themes covered by JBC.

Assembled by the editors of JBC

Published January 2015

Best of 2013

Best of 2013

This issue announces the “Best of JBC” articles of 2013, selected to represent each of the broad themes covered by JBC, and includes four podcasts that dive deeper into some of the articles' contents.

Assembled by the editors of JBC

Published January 2014

 Best of 2012

Best of 2012

This issue announces the “Best of JBC” articles of 2012, selected to represent each of the broad themes covered by JBC.

Assembled by the editors of JBC

Published January 2013

Best of 2011

Best of 2011

This issue announces the “Best of JBC” articles of 2011, selected to represent each of the broad themes covered by JBC.

Assembled by the editors of JBC

Published January 2012

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